Next Sunday night (US time), about 9 AM Monday Stockholm time, the Karolinska is going to wake up one to three biologists and announce they have won the Nobel Prize.
Thompson Reuters has their list based on citation, I call this hokey.
Here is Thompsons’s list with my thumb added where I think they may be right. Then I added my own guesses.
Finally, I have added some UW names I think may want to wait for the phone call.
This is unlikely.
Cell Adhesion
SMS: Hynes was not among the discovers of the integrins and his excellent work has not been unique. Ruosalahti is rumored to want the prize BUT his word on the peptide RGD has not yielded much clinical result. Personally, I would put Mark Ginsberg here, his work on what he called cytoadhesins was seminal to the huge world of integrin signalling. Tekeichi did discover the cadherins but a nobel for them surely would need to include a prize for the signalling pathways that use beta catenin. I would also include John Harlan since he, with my wife as first author, described the first adhesion molecule that controls inflammatory responses.
This is unlikley
Cell Signaling and Control
SMS: I doubt this too, There already have been prizes for the signalling pathways controlled by the tyrosine kinases as well as for the ligands that stimulate them. The ony way I could see this is with Brian Druker.
Genetic Regulation
And here is my list:
Shinya Yamanaka, Irv Weissman, Reudi Yaenish Tokyo, Gladstone, Stanford, MIT the stem cell
Reudi Jaenish, MIY Beatrice Mintz, Fox Chase the trangenic mouse.
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A personal note: Goran Hansson, the Secretary General of the Nobel Committee, seated in the bottom middle of the photograph, is a former fellow of mine, a greatly admired colleague and a dear friend. Goran’s own work has been on the roll of the immune system in the etiology of vascular diseases, especially atherosclerosis.
- Eric Lander, Phil Green MIT, Harvard, UW human genome project
Ruslan Medzhitov Yale The innate immune system.
Jerry Nepom, UW, Ake Lernmark Upsalla, the type 1 diabets gene
- Brian Druker, anti kinase therapy in cancer Oregon (see comment about Tony Hunter above).
Earl Davies, UW, the coagulation cascade.
These UW Names Here Deserve Nobels: