About 9 AM Stockholm time Monday, the Karolinska is going to wake up one to three biologists and announce they have won the Nobel Prize.
Thompson Reuters has their list based on citation, I call this hokey.
Here is Thompsons’s list with my thumb added in an appropriate direction where I think Reuters may be right or wrong. Then I added my own gueses. Finally, I have added some UW names I think may want to wait for the phone call.
 C. David AllisTri-Institutional Professor and Joy and Jack Fishman Professor Head, Laboratory of Chromatin Biology and Epigenetics Rockefeller University New York, New York, USA -and- Michael Grunstein |
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Anthony “Tony” R. Hunter comment: The tyrosine kinase receptor work was good, but a LOT mor people have been important beside these two.
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 Richard O. HynesDaniel K. Ludwig Professor for Cancer Research David H. Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Howard Hughes Medical Institute Investigator Cambridge, Massachusetts, USA -and- Erkki Ruoslahti Distinguished Professor, Center for Nanomedicine Sanford-Burnham Medical Research Institute University of California Santa Barbara Santa Barbara, California, USA -and- Masatoshi Takeichi Director, RIKEN Center for Developmental Biology Kobe, Japan For pioneering discoveries of cell adhesion molecules, Hynes and Ruoslahti for integrins and Takeichi for cadherins comment: This list is more reflctive of campaigning for the Nobel than for achievement. Neither Hynes not Ruoslahti “disvoered” the integrins. Ruosalahti’s work with the RGD peptides is imortnat, but the perosn whose work was most seminal in understanding the integrins was Mark Ginsberg. who wrote the seminal papers on signalling. Takeshi’s discovery of clacumependent adhesion molecules is a unique find, but others are responsible for the broadening of this to include whole classes of cadherins, identify their key roles in development, an cefine the beta catrenin signaling pathway. Richard Hynes work is good, solif work on the integrins but he is only listed here because he conferred the name “integrin.” From a UW point of view, John Harlan should have been included in any ist of adherance molecules since hid discovery of the first leukocyte adhesion molecule, a key discovery in inflammation. My wife was first author on that paper! |
And here is my list:
- Shinya Yamanaka, Irv Weissman, Reudi Yaenish Tokyo, Gladstone, Stanford, MIT the stem cell
- Eric Lander, Phil Green MIT, Harvard, UW human genome project
- Ruslan Medzhitov Yale The innate immune system.
- Brian Druker, anti kinase therapy in cancer Oregon
These UW Names Deserve Nobels: